Clubfoot Research Studies & Papers by Topic | Non-Surgical Clubfoot Treatment - The Ponseti Method Clubfoot Research Studies & Papers by Topic | Non-Surgical Clubfoot Treatment - The Ponseti Method

Clubfoot Research Studies & Papers by Topic

If you find a study that should be on this page, please send us the title, link, and abstract, and we will review it for addition to this page. New links are added regularly as they are discovered. Beware, should you find yourself collecting study links. The study rabbit hole can get deep and it seems to involve a lot of tabs!

Some of our favorite doctors and caregivers are highlighted with italics and bold type. Please use Use ctrl+F or cmd+F to find a word or phrase on this page before emailing us a link to a new study to include. See our contact page.


Some of these full texts aren't available without a subscription. Your doctor likely can get access and can print a study for you if you can't find another online source for the full texts. When possible, the full text article has been linked. If you are able to find the full text or the abstract of any of these that are missing texts, please contact us with the link so we can update this page.

These categories are best perused by using the Main Menu at the top of the page, under "Resources". However for quick reference, this page also shows every study.

*Click a topic to show the study links. Click the link below the title to go to the study category page itself.

**All studies and papers are sorted by date, with the most recent at the top**

***FIND in PAGE does not work when the topics are collapsed. To use find on this page AND have it include all topics and studies, all the topics must be expanded. Apologies for this inconvenience. Use Ctrl+F (Windows) or Cmd+F (Mac) to "Find" key words in the titles of these studies. On mobile, use the "Find in page" option. You can also search by author name.***

Go to the Searchable - All Clubfoot Research Studies page


This page is for searching all the studies and articles listed on this website. On this page each topic heading has been expanded. This makes the entire studies listing searchable. It also makes for a very long page that can be difficult for some visitors to use for browsing. For more practical and user friendly browsing, please see the All Clubfoot Studies page, or use the main menu to drill down into a specific topic or category.

***Use ctrl+F (Windows) or cmd+F (Mac) to "Find" key words in the titles of these studies.


Desktop Browser Find In Page (Control+F) - showing 1 of 55 results


On mobile, use "Find in page".

You can also search by author name or year published.***

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Select "Find In Page" - Then search for your term

Go to the Dr. Ponseti's Studies page


The 30 Year Study

(that fueled the parental revolution and was the inspiration for Dr. Ponseti's book, Congenital Clubfoot: Fundamentals of Treatment, published in 1996)


Modification vs Strict Adherence to Ponseti Method

Clubfoot In History

Ponseti Method Training


Go to the Achilles Tenotomy Studies page


Botox for tendon lengthening.


Using Botox to Treat Patients With Idiopathic Clubfoot This page lists an ongoing and actively recruiting study that Dr. Christine Alvarez is the principle researcher. This link is listed only for informational purposes. The study is not guaranteed to be ongoing however as of July 2025 the page shows as active and recruiting. For participants 12 and younger, in Vancouver, BC Canada.

Botulinum toxin in treatment of clubfoot relapse - Patent application by Chrinstine Alvarez - status: Abandoned


Go to the Age When Treatment Begins Studies page


*See the "Neglected Clubfoot" section for papers studying the Ponseti Method for children of walking age, or older.


Go to the Anterior Tibialis Tendon Transfer - ATTT/TATT page



Go to the Biology and Etiology of Clubfoot Studies page



Go to the Bracing Studies page


"The goal of the extensive bracing regime is to prevent recurrence by opposing the deforming forces at the medial ankle–foot joints that persist or reoccur after initial correction of the clubfoot" (Ponseti 2002, Dobbs and Gurnett 2009, Hosseinzadeh et al. 2017).


Bracing Comparisons


Foot Abduction Brace/Bar (FAB, BnB, Boots & Bar, DBB)


Bracing Time/Length & Compliance


Abduction Dorsiflexion Mechanism (ADM)

ADM prospective studies

*This is not a published paper or confirmed study; but it might be ongoing. If you wish to participate see this page and email the study contact.
Feasibility of Other Orthosis for Talipes (FOOT) trial - Nigel Kiely - United Kingdom


Ankle Foot Orthosis (AFO)


Go to the Casting Studies page



Accelerated or "Fast" Casting


Go to the Complex and Atypical Clubfoot Studies page



Go to the Clubfoot Score/Assessments and Classifications Studies (Severity) page


Clubfoot Severity Scoring/Classification (initial assessment)

letter to the editor re: Predicting the Need for Surgical Intervention in Patients With Idiopathic Clubfoot June 2016 - Aydin, Bahattin K. MD; Sofu, Hakan MD


Ultrasound Assessment of Clubfoot Severity


Clubfoot Assessment (after treatment)


Go to the Delayed Presenting Clubfoot - DPC (Neglected & Untreated) Clubfoot Studies page


**Clubfoot is often left untreated in some underdeveloped nations and it can take some years to begin treatment. Usually patients are over 6 months to a year old, but often they are much older.

NOTE: This paper follows a 24 year old untreated/neglected university student treated with Ponseti Method

Iliazarov Technique/Frame/External Fixators/Taylor Spacial Frame


Go to the Development & Motor Skills Studies page



Go to the Dorsiflexion Research page




Go to the External Frame Studies page


Iliazarov Technique/Frame/External Fixators/Taylor Spacial Frame


Go to the False Positives or Missed Positives for Clubfoot on Ultrasound page



Go to the Flat Top Talus Studies page


Functional Implications of Flat-Topped Talus Following Treatment of Idiopathic Clubfoot Deformity - March 2023 - Matthew J Siebert, Jacob R Zide, Claire Shivers, Kirsten Tulchin-Francis, Wilshaw Stevens, Justine Borchard, Anthony I Riccio

Flat-Top/Flattened Talus/Talar Dome

Talar Deformity & Flattening


Go to the Foot Bones (Talus) Studies page


Flat-Top/Flattened Talus/Talar Dome

Talar Deformity & Flattening


Go to the Foot Length & Calf Muscle Discrepancy Studies page



Go to the Gait Studies page



Go to the Gender Studies page



Go to the General Clubfoot Studies & Ponseti vs Surgery Studies page



Go to the Genetics Studies, Hereditary & Other Risk Factors with Associated Clubfoot page


Associated Risk Factors (potential)


Go to the Hip Dysplasia Clubfoot Studies page


This website has comprehensive information about hip ultrasound results. Radiology Assistant


Go to the HyperMobility/HyperFlexibility Studies page



Go to the Locale Specific Studies page



Go to the Long-Term Follow Up Studies page



Go to the Non-Idiopathic Studies (Syndromic) & Clubfoot Associated (Neuro, Genetic, etc.) page


Click into the heading below for more information from this paper

The following is a listing of non-idiopathic conditions from the sample of participants from the above research paper. All the patients were treated at Shriners St. Louis by Dr. Matthew Dobbs.

This is not an exhaustive list of associated or concurrent conditions, however it may help you understand the incidence of each listed condition in a sample of 84 total participants with an additional condition other than clubfoot. Please see the Discussion portion of the study linked above for more detailed information on rates seen in studies from global samples published before 2008. Rates for idiopathic vs non-idiopathic have been identified in other research since this paper was published and the general consensus at the time of this writing is that about 20% of clubfoot is non-idiopathic.


Etiologies of non-idiopathic CTEV (additional malformations, chromosomal abnormalities, genetic syndromes)

Central nervous system, n (%) 12/84 (14)

Dandy Walker 2
Septo-optic dysplasia 1
Perisylvian syndrome 2
Neuroblastoma 1
Choroid plexus papilloma 1
Other 5

Spinal cord, n (%) 19/84 (23)

Myelomeningocele 17
Spinal muscular atrophy-like (SMN negative) 1
Tethered cord 1

Muscle, n (%) 15/84 (18)

Distal arthrogryposis 6
Arthrogryposis multiplex 4
Congenital myotonic dystrophy 3
Congenital muscular dystrophy 2

Chromosomal abnormality, n (%) 10/84 (12)

Trisomy 18 2
Trisomy 21 1
Ring chromosome 18 1
Partial trisomy 4, monosomy X 1
Partial trisomy 1q and monosomy 10q 1
Partial trisomy 13q and monosomy 5p 1
22q11.2 deletion 2
Subtelomeric deletion 13q 1

Known genetic syndromes, n (%) 5/84 (6)

Costello syndrome 1
Carpenter syndrome 1
Toriello Carey syndrome 1
Osteogenesis imperfecta 1
X-linked chondrodysplasia punctata 1

Probable genetic syndrome, n (%) 19/84 (23)
Orthopedic n (%) (fibular hemimelia, polydactyly, hip dysplasia, ulnar longitudinal deficiency) 6/84 (7)
Multiple congenital anomaly 13/84 (15)
Amniotic band sequence, n (%) 4/84 (5)




Arthrogryposis


Myelomeningocele


Spina Bifida


Tethered Cord

Amniotic Band Syndrome


Polydactyly


Developmental Hip Dysplasia, Congenital Muscular Torticollis

See the Hip Dysplasia & Clubfoot Studies page for these studies.

Why? - According to all but one paper listed at the link above, Developmental Hip Dysplasia (DDH) is not at any higher risk with clubfoot. Standard clinical exams (normal exam the pediatrician does to check the hips) are sufficient for any screening for DDH, and routine ultrasound screening is not considered warranted or cost effective.

Other specific disorders or conditions

  • Saul-Wilson Syndrome Jan 2020 - Carlos Ferreira Margaret P Adam, David B Everman, Ghayda M Mirzaa, Roberta A Pagon, Stephanie E Wallace, Lora JH Bean, Karen W Gripp, Anne Amemiya

Go to the Other Non-Surgical Methods Studies page


Multi-Method Comparisons


French Functional


Copenhagen

Ram's Taping


Kite

Others


Go to the Other Talipes Types - Vertical Talus (Rocker Bottom), Calcaneovalgus, Calcaneovarus, Etc. page



Go to the ​Physical Abilities & Sport Studies page



Go to the Physiotherapy Studies (PT) page



Go to the Relapse & Recurrent Clubfoot Studies page



NOTE: To understand what Concomitant Talocalcaneal Coalition is, this article from Dr. Vincent Mosca has a video showing the surgery to remove the tissue between the tarsal bones in a child who does not have clubfoot. Talocalcaneal coalition resection 2024 - Vincent S. Mosca MD, Javier Masquijo MD

NOTE: This paper discusses relapse as associated with Pirani and Dimeglio scores

NOTE: This paper shows awesome images of what relapse looks like.

Note: This paper uses data from Pirani score, number of casts, and bracing compliance to get their results. Therefore it will be listed in 3 categories on this page.

This information was initially presented at the 4th International Clubfoot Meeting in Istanbul, Turkey and the Annual Meeting of the American Academy of Pediatrics in Washington D.C. in 2005.


Relapse Assessment


Clubfoot Relapse Surgery (Anterior Tibialis Tendon Transfer - ATTT/TATT/ATT)

NOTE: This full text paper shows both still images and video of the ATTT surgery

Other Relapse Surgery


Go to the Reviews of Clubfoot Studies page


Editor Note: This literature review shows improper casts.


Go to the Severity Studies page



Go to the Scans/Imaging Studies & Articles (Ultrasound, X-Ray, MRI, CT - Mother or Child) page



Go to the Study Standards Papers page



Go to the Surgical Correction for Clubfoot Studies page


**Studies associated with initial surgical correction - Non-Ponseti Method. Some are quite old, Some do not have text at all. Full texts can usually be specifically requested.

The following link is a PDF file of a "book" compilation of many studies and papers describing mostly surgical methods and treatments for clubfoot up until the time of it's writing in 1993. There is a small section near the end discussing "conservative" treatments but does not mention any non-surgical methods by name. Dr. Ponseti is referenced 20 times, only in citations for his papers. If you want to find out more about your specific surgical method, chances are there are pictures and descriptions of it within this large document.

This document is 27MB in size and downloads as a PDF to your device by default. If you would like to load a 16mb file inline and view it in your browser without downloading the file, use this link. Due to it's size, it will first throw an error in your browser, but if you are patient it will eventually load.



Go to the Unilateral and Bilateral Studies page



Go to the Valgus Overcorrection Studies page


Valgus Overcorrection

NOTE: The above paper looked at older feet (18y+) treated with surgical correction.

NOTE: The above paper looks at "overcorrection" in older feet treated with surgical correction pre 2000's. Will need a full text version to know more. This link is not that.

NOTE: The above paper looks at "overcorrection" in older feet treated with surgical correction pre 2000's. Will need a full text version to know more. This link is not that.

NOTE: The above paper details a surgical approach to treatment for valgus overcorrection in older feet treated with surgical correction pre 2000's.


Go to the Vertical Talus (Congenital) - Congenital Rocker Bottom page




Go to the All Studies page


**Click a topic to show all the study links for that category.

Closed Study Topic

**Click the link below the topic title to go to the study category page itself.

Opened Study Topic
  • Some of our favorite doctors and caregivers are highlighted with italics and bold type.
  • Some of these full texts aren't available without a subscription. Your doctor likely can get access and can print a study for you if you can't find another online source for the full texts.
  • When possible, the full text article has been linked. If you are able to find the full text or the abstract of any of these that are missing texts, please contact us with the link so we can update this page. 

*All studies and papers are sorted by date, with the most recent at the top*

**FIND in PAGE and other FIND actions do NOT work when the topics are collapsed.

To use search functions on this listing, please go to the Searchable All Cubfoot Studies page.

If you find a study that should be on this page, please send us the title, link, or abstract, and we will review it for addition to this page. New links are added regularly as they are discovered.

Please use Use ctrl+F, cmd+F, or "Find in Page" (on mobile) on the Searchable All Cubfoot Studies Page to check the entire study collection before requesting that a new paper be added.

Go to the Dr. Ponseti's Studies page


The 30 Year Study

(that fueled the parental revolution and was the inspiration for Dr. Ponseti's book, Congenital Clubfoot: Fundamentals of Treatment, published in 1996)


Modification vs Strict Adherence to Ponseti Method

Clubfoot In History

Ponseti Method Training


Go to the Achilles Tenotomy Studies page


Botox for tendon lengthening.


Using Botox to Treat Patients With Idiopathic Clubfoot This page lists an ongoing and actively recruiting study that Dr. Christine Alvarez is the principle researcher. This link is listed only for informational purposes. The study is not guaranteed to be ongoing however as of July 2025 the page shows as active and recruiting. For participants 12 and younger, in Vancouver, BC Canada.

Botulinum toxin in treatment of clubfoot relapse - Patent application by Chrinstine Alvarez - status: Abandoned


Go to the Age When Treatment Begins Studies page


*See the "Neglected Clubfoot" section for papers studying the Ponseti Method for children of walking age, or older.


Go to the Anterior Tibialis Tendon Transfer - ATTT/TATT page



Go to the Biology and Etiology of Clubfoot Studies page



Go to the Bracing Studies page


"The goal of the extensive bracing regime is to prevent recurrence by opposing the deforming forces at the medial ankle–foot joints that persist or reoccur after initial correction of the clubfoot" (Ponseti 2002, Dobbs and Gurnett 2009, Hosseinzadeh et al. 2017).


Bracing Comparisons


Foot Abduction Brace/Bar (FAB, BnB, Boots & Bar, DBB)


Bracing Time/Length & Compliance


Abduction Dorsiflexion Mechanism (ADM)

ADM prospective studies

*This is not a published paper or confirmed study; but it might be ongoing. If you wish to participate see this page and email the study contact.
Feasibility of Other Orthosis for Talipes (FOOT) trial - Nigel Kiely - United Kingdom


Ankle Foot Orthosis (AFO)


Go to the Casting Studies page



Accelerated or "Fast" Casting


Go to the Complex and Atypical Clubfoot Studies page



Go to the Clubfoot Score/Assessments and Classifications Studies (Severity) page


Clubfoot Severity Scoring/Classification (initial assessment)

letter to the editor re: Predicting the Need for Surgical Intervention in Patients With Idiopathic Clubfoot June 2016 - Aydin, Bahattin K. MD; Sofu, Hakan MD


Ultrasound Assessment of Clubfoot Severity


Clubfoot Assessment (after treatment)


Go to the Delayed Presenting Clubfoot - DPC (Neglected & Untreated) Clubfoot Studies page


**Clubfoot is often left untreated in some underdeveloped nations and it can take some years to begin treatment. Usually patients are over 6 months to a year old, but often they are much older.

NOTE: This paper follows a 24 year old untreated/neglected university student treated with Ponseti Method

Iliazarov Technique/Frame/External Fixators/Taylor Spacial Frame


Go to the Development & Motor Skills Studies page



Go to the Dorsiflexion Research page




Go to the External Frame Studies page


Iliazarov Technique/Frame/External Fixators/Taylor Spacial Frame


Go to the False Positives or Missed Positives for Clubfoot on Ultrasound page



Go to the Flat Top Talus Studies page


Functional Implications of Flat-Topped Talus Following Treatment of Idiopathic Clubfoot Deformity - March 2023 - Matthew J Siebert, Jacob R Zide, Claire Shivers, Kirsten Tulchin-Francis, Wilshaw Stevens, Justine Borchard, Anthony I Riccio

Flat-Top/Flattened Talus/Talar Dome

Talar Deformity & Flattening


Go to the Foot Bones (Talus) Studies page


Flat-Top/Flattened Talus/Talar Dome

Talar Deformity & Flattening


Go to the Foot Length & Calf Muscle Discrepancy Studies page



Go to the Gait Studies page



Go to the Gender Studies page



Go to the General Clubfoot Studies & Ponseti vs Surgery Studies page



Go to the Genetics Studies, Hereditary & Other Risk Factors with Associated Clubfoot page


Associated Risk Factors (potential)


Go to the Hip Dysplasia Clubfoot Studies page


This website has comprehensive information about hip ultrasound results. Radiology Assistant


Go to the HyperMobility/HyperFlexibility Studies page



Go to the Locale Specific Studies page



Go to the Long-Term Follow Up Studies page



Go to the Non-Idiopathic Studies (Syndromic) & Clubfoot Associated (Neuro, Genetic, etc.) page


Click into the heading below for more information from this paper

The following is a listing of non-idiopathic conditions from the sample of participants from the above research paper. All the patients were treated at Shriners St. Louis by Dr. Matthew Dobbs.

This is not an exhaustive list of associated or concurrent conditions, however it may help you understand the incidence of each listed condition in a sample of 84 total participants with an additional condition other than clubfoot. Please see the Discussion portion of the study linked above for more detailed information on rates seen in studies from global samples published before 2008. Rates for idiopathic vs non-idiopathic have been identified in other research since this paper was published and the general consensus at the time of this writing is that about 20% of clubfoot is non-idiopathic.


Etiologies of non-idiopathic CTEV (additional malformations, chromosomal abnormalities, genetic syndromes)

Central nervous system, n (%) 12/84 (14)

Dandy Walker 2
Septo-optic dysplasia 1
Perisylvian syndrome 2
Neuroblastoma 1
Choroid plexus papilloma 1
Other 5

Spinal cord, n (%) 19/84 (23)

Myelomeningocele 17
Spinal muscular atrophy-like (SMN negative) 1
Tethered cord 1

Muscle, n (%) 15/84 (18)

Distal arthrogryposis 6
Arthrogryposis multiplex 4
Congenital myotonic dystrophy 3
Congenital muscular dystrophy 2

Chromosomal abnormality, n (%) 10/84 (12)

Trisomy 18 2
Trisomy 21 1
Ring chromosome 18 1
Partial trisomy 4, monosomy X 1
Partial trisomy 1q and monosomy 10q 1
Partial trisomy 13q and monosomy 5p 1
22q11.2 deletion 2
Subtelomeric deletion 13q 1

Known genetic syndromes, n (%) 5/84 (6)

Costello syndrome 1
Carpenter syndrome 1
Toriello Carey syndrome 1
Osteogenesis imperfecta 1
X-linked chondrodysplasia punctata 1

Probable genetic syndrome, n (%) 19/84 (23)
Orthopedic n (%) (fibular hemimelia, polydactyly, hip dysplasia, ulnar longitudinal deficiency) 6/84 (7)
Multiple congenital anomaly 13/84 (15)
Amniotic band sequence, n (%) 4/84 (5)




Arthrogryposis


Myelomeningocele


Spina Bifida


Tethered Cord

Amniotic Band Syndrome


Polydactyly


Developmental Hip Dysplasia, Congenital Muscular Torticollis

See the Hip Dysplasia & Clubfoot Studies page for these studies.

Why? - According to all but one paper listed at the link above, Developmental Hip Dysplasia (DDH) is not at any higher risk with clubfoot. Standard clinical exams (normal exam the pediatrician does to check the hips) are sufficient for any screening for DDH, and routine ultrasound screening is not considered warranted or cost effective.

Other specific disorders or conditions

  • Saul-Wilson Syndrome Jan 2020 - Carlos Ferreira Margaret P Adam, David B Everman, Ghayda M Mirzaa, Roberta A Pagon, Stephanie E Wallace, Lora JH Bean, Karen W Gripp, Anne Amemiya

Go to the Other Non-Surgical Methods Studies page


Multi-Method Comparisons


French Functional


Copenhagen

Ram's Taping


Kite

Others


Go to the Other Talipes Types - Vertical Talus (Rocker Bottom), Calcaneovalgus, Calcaneovarus, Etc. page



Go to the ​Physical Abilities & Sport Studies page



Go to the Physiotherapy Studies (PT) page



Go to the Relapse & Recurrent Clubfoot Studies page



NOTE: To understand what Concomitant Talocalcaneal Coalition is, this article from Dr. Vincent Mosca has a video showing the surgery to remove the tissue between the tarsal bones in a child who does not have clubfoot. Talocalcaneal coalition resection 2024 - Vincent S. Mosca MD, Javier Masquijo MD

NOTE: This paper discusses relapse as associated with Pirani and Dimeglio scores

NOTE: This paper shows awesome images of what relapse looks like.

Note: This paper uses data from Pirani score, number of casts, and bracing compliance to get their results. Therefore it will be listed in 3 categories on this page.

This information was initially presented at the 4th International Clubfoot Meeting in Istanbul, Turkey and the Annual Meeting of the American Academy of Pediatrics in Washington D.C. in 2005.


Relapse Assessment


Clubfoot Relapse Surgery (Anterior Tibialis Tendon Transfer - ATTT/TATT/ATT)

NOTE: This full text paper shows both still images and video of the ATTT surgery

Other Relapse Surgery


Go to the Reviews of Clubfoot Studies page


Editor Note: This literature review shows improper casts.


Go to the Severity Studies page



Go to the Scans/Imaging Studies & Articles (Ultrasound, X-Ray, MRI, CT - Mother or Child) page



Go to the Study Standards Papers page



Go to the Surgical Correction for Clubfoot Studies page


**Studies associated with initial surgical correction - Non-Ponseti Method. Some are quite old, Some do not have text at all. Full texts can usually be specifically requested.

The following link is a PDF file of a "book" compilation of many studies and papers describing mostly surgical methods and treatments for clubfoot up until the time of it's writing in 1993. There is a small section near the end discussing "conservative" treatments but does not mention any non-surgical methods by name. Dr. Ponseti is referenced 20 times, only in citations for his papers. If you want to find out more about your specific surgical method, chances are there are pictures and descriptions of it within this large document.

This document is 27MB in size and downloads as a PDF to your device by default. If you would like to load a 16mb file inline and view it in your browser without downloading the file, use this link. Due to it's size, it will first throw an error in your browser, but if you are patient it will eventually load.



Go to the Unilateral and Bilateral Studies page



Go to the Valgus Overcorrection Studies page


Valgus Overcorrection

NOTE: The above paper looked at older feet (18y+) treated with surgical correction.

NOTE: The above paper looks at "overcorrection" in older feet treated with surgical correction pre 2000's. Will need a full text version to know more. This link is not that.

NOTE: The above paper looks at "overcorrection" in older feet treated with surgical correction pre 2000's. Will need a full text version to know more. This link is not that.

NOTE: The above paper details a surgical approach to treatment for valgus overcorrection in older feet treated with surgical correction pre 2000's.


Go to the Vertical Talus (Congenital) - Congenital Rocker Bottom page



The 97 most frequently used keywords in published articles on clubfoot -

The 97 most frequently used keywords in published articles on clubfoot - Clubfoot from past to the present: A bibliometric analysis with global productivity and research trends - 2023 - Hakan Yolaçan, MD, Serkan Güler, MD, Ramadan Özmanevra, MD


Go to the Dr. Ponseti's Studies page


The 30 Year Study

(that fueled the parental revolution and was the inspiration for Dr. Ponseti's book, Congenital Clubfoot: Fundamentals of Treatment, published in 1996)


Modification vs Strict Adherence to Ponseti Method

Clubfoot In History

Ponseti Method Training


Go to the Achilles Tenotomy Studies page


Botox for tendon lengthening.


Using Botox to Treat Patients With Idiopathic Clubfoot This page lists an ongoing and actively recruiting study that Dr. Christine Alvarez is the principle researcher. This link is listed only for informational purposes. The study is not guaranteed to be ongoing however as of July 2025 the page shows as active and recruiting. For participants 12 and younger, in Vancouver, BC Canada.

Botulinum toxin in treatment of clubfoot relapse - Patent application by Chrinstine Alvarez - status: Abandoned


Go to the Age When Treatment Begins Studies page


*See the "Neglected Clubfoot" section for papers studying the Ponseti Method for children of walking age, or older.


Go to the Anterior Tibialis Tendon Transfer - ATTT/TATT page



Go to the Biology and Etiology of Clubfoot Studies page



Go to the Bracing Studies page


"The goal of the extensive bracing regime is to prevent recurrence by opposing the deforming forces at the medial ankle–foot joints that persist or reoccur after initial correction of the clubfoot" (Ponseti 2002, Dobbs and Gurnett 2009, Hosseinzadeh et al. 2017).


Bracing Comparisons


Foot Abduction Brace/Bar (FAB, BnB, Boots & Bar, DBB)


Bracing Time/Length & Compliance


Abduction Dorsiflexion Mechanism (ADM)

ADM prospective studies

*This is not a published paper or confirmed study; but it might be ongoing. If you wish to participate see this page and email the study contact.
Feasibility of Other Orthosis for Talipes (FOOT) trial - Nigel Kiely - United Kingdom


Ankle Foot Orthosis (AFO)


Go to the Casting Studies page



Accelerated or "Fast" Casting


Go to the Complex and Atypical Clubfoot Studies page



Go to the Clubfoot Score/Assessments and Classifications Studies (Severity) page


Clubfoot Severity Scoring/Classification (initial assessment)

letter to the editor re: Predicting the Need for Surgical Intervention in Patients With Idiopathic Clubfoot June 2016 - Aydin, Bahattin K. MD; Sofu, Hakan MD


Ultrasound Assessment of Clubfoot Severity


Clubfoot Assessment (after treatment)


Go to the Delayed Presenting Clubfoot - DPC (Neglected & Untreated) Clubfoot Studies page


**Clubfoot is often left untreated in some underdeveloped nations and it can take some years to begin treatment. Usually patients are over 6 months to a year old, but often they are much older.

NOTE: This paper follows a 24 year old untreated/neglected university student treated with Ponseti Method

Iliazarov Technique/Frame/External Fixators/Taylor Spacial Frame


Go to the Development & Motor Skills Studies page



Go to the Dorsiflexion Research page




Go to the External Frame Studies page


Iliazarov Technique/Frame/External Fixators/Taylor Spacial Frame


Go to the False Positives or Missed Positives for Clubfoot on Ultrasound page



Go to the Flat Top Talus Studies page


Functional Implications of Flat-Topped Talus Following Treatment of Idiopathic Clubfoot Deformity - March 2023 - Matthew J Siebert, Jacob R Zide, Claire Shivers, Kirsten Tulchin-Francis, Wilshaw Stevens, Justine Borchard, Anthony I Riccio

Flat-Top/Flattened Talus/Talar Dome

Talar Deformity & Flattening


Go to the Foot Bones (Talus) Studies page


Flat-Top/Flattened Talus/Talar Dome

Talar Deformity & Flattening


Go to the Foot Length & Calf Muscle Discrepancy Studies page



Go to the Gait Studies page



Go to the Gender Studies page



Go to the General Clubfoot Studies & Ponseti vs Surgery Studies page



Go to the Genetics Studies, Hereditary & Other Risk Factors with Associated Clubfoot page


Associated Risk Factors (potential)


Go to the Hip Dysplasia Clubfoot Studies page


This website has comprehensive information about hip ultrasound results. Radiology Assistant


Go to the HyperMobility/HyperFlexibility Studies page



Go to the Locale Specific Studies page



Go to the Long-Term Follow Up Studies page



Go to the Non-Idiopathic Studies (Syndromic) & Clubfoot Associated (Neuro, Genetic, etc.) page


Click into the heading below for more information from this paper

The following is a listing of non-idiopathic conditions from the sample of participants from the above research paper. All the patients were treated at Shriners St. Louis by Dr. Matthew Dobbs.

This is not an exhaustive list of associated or concurrent conditions, however it may help you understand the incidence of each listed condition in a sample of 84 total participants with an additional condition other than clubfoot. Please see the Discussion portion of the study linked above for more detailed information on rates seen in studies from global samples published before 2008. Rates for idiopathic vs non-idiopathic have been identified in other research since this paper was published and the general consensus at the time of this writing is that about 20% of clubfoot is non-idiopathic.


Etiologies of non-idiopathic CTEV (additional malformations, chromosomal abnormalities, genetic syndromes)

Central nervous system, n (%) 12/84 (14)

Dandy Walker 2
Septo-optic dysplasia 1
Perisylvian syndrome 2
Neuroblastoma 1
Choroid plexus papilloma 1
Other 5

Spinal cord, n (%) 19/84 (23)

Myelomeningocele 17
Spinal muscular atrophy-like (SMN negative) 1
Tethered cord 1

Muscle, n (%) 15/84 (18)

Distal arthrogryposis 6
Arthrogryposis multiplex 4
Congenital myotonic dystrophy 3
Congenital muscular dystrophy 2

Chromosomal abnormality, n (%) 10/84 (12)

Trisomy 18 2
Trisomy 21 1
Ring chromosome 18 1
Partial trisomy 4, monosomy X 1
Partial trisomy 1q and monosomy 10q 1
Partial trisomy 13q and monosomy 5p 1
22q11.2 deletion 2
Subtelomeric deletion 13q 1

Known genetic syndromes, n (%) 5/84 (6)

Costello syndrome 1
Carpenter syndrome 1
Toriello Carey syndrome 1
Osteogenesis imperfecta 1
X-linked chondrodysplasia punctata 1

Probable genetic syndrome, n (%) 19/84 (23)
Orthopedic n (%) (fibular hemimelia, polydactyly, hip dysplasia, ulnar longitudinal deficiency) 6/84 (7)
Multiple congenital anomaly 13/84 (15)
Amniotic band sequence, n (%) 4/84 (5)




Arthrogryposis


Myelomeningocele


Spina Bifida


Tethered Cord

Amniotic Band Syndrome


Polydactyly


Developmental Hip Dysplasia, Congenital Muscular Torticollis

See the Hip Dysplasia & Clubfoot Studies page for these studies.

Why? - According to all but one paper listed at the link above, Developmental Hip Dysplasia (DDH) is not at any higher risk with clubfoot. Standard clinical exams (normal exam the pediatrician does to check the hips) are sufficient for any screening for DDH, and routine ultrasound screening is not considered warranted or cost effective.

Other specific disorders or conditions

  • Saul-Wilson Syndrome Jan 2020 - Carlos Ferreira Margaret P Adam, David B Everman, Ghayda M Mirzaa, Roberta A Pagon, Stephanie E Wallace, Lora JH Bean, Karen W Gripp, Anne Amemiya

Go to the Other Non-Surgical Methods Studies page


Multi-Method Comparisons


French Functional


Copenhagen

Ram's Taping


Kite

Others


Go to the Other Talipes Types - Vertical Talus (Rocker Bottom), Calcaneovalgus, Calcaneovarus, Etc. page



Go to the ​Physical Abilities & Sport Studies page



Go to the Physiotherapy Studies (PT) page



Go to the Relapse & Recurrent Clubfoot Studies page



NOTE: To understand what Concomitant Talocalcaneal Coalition is, this article from Dr. Vincent Mosca has a video showing the surgery to remove the tissue between the tarsal bones in a child who does not have clubfoot. Talocalcaneal coalition resection 2024 - Vincent S. Mosca MD, Javier Masquijo MD

NOTE: This paper discusses relapse as associated with Pirani and Dimeglio scores

NOTE: This paper shows awesome images of what relapse looks like.

Note: This paper uses data from Pirani score, number of casts, and bracing compliance to get their results. Therefore it will be listed in 3 categories on this page.

This information was initially presented at the 4th International Clubfoot Meeting in Istanbul, Turkey and the Annual Meeting of the American Academy of Pediatrics in Washington D.C. in 2005.


Relapse Assessment


Clubfoot Relapse Surgery (Anterior Tibialis Tendon Transfer - ATTT/TATT/ATT)

NOTE: This full text paper shows both still images and video of the ATTT surgery

Other Relapse Surgery


Go to the Reviews of Clubfoot Studies page


Editor Note: This literature review shows improper casts.


Go to the Severity Studies page



Go to the Scans/Imaging Studies & Articles (Ultrasound, X-Ray, MRI, CT - Mother or Child) page



Go to the Study Standards Papers page



Go to the Surgical Correction for Clubfoot Studies page


**Studies associated with initial surgical correction - Non-Ponseti Method. Some are quite old, Some do not have text at all. Full texts can usually be specifically requested.

The following link is a PDF file of a "book" compilation of many studies and papers describing mostly surgical methods and treatments for clubfoot up until the time of it's writing in 1993. There is a small section near the end discussing "conservative" treatments but does not mention any non-surgical methods by name. Dr. Ponseti is referenced 20 times, only in citations for his papers. If you want to find out more about your specific surgical method, chances are there are pictures and descriptions of it within this large document.

This document is 27MB in size and downloads as a PDF to your device by default. If you would like to load a 16mb file inline and view it in your browser without downloading the file, use this link. Due to it's size, it will first throw an error in your browser, but if you are patient it will eventually load.



Go to the Unilateral and Bilateral Studies page



Go to the Valgus Overcorrection Studies page


Valgus Overcorrection

NOTE: The above paper looked at older feet (18y+) treated with surgical correction.

NOTE: The above paper looks at "overcorrection" in older feet treated with surgical correction pre 2000's. Will need a full text version to know more. This link is not that.

NOTE: The above paper looks at "overcorrection" in older feet treated with surgical correction pre 2000's. Will need a full text version to know more. This link is not that.

NOTE: The above paper details a surgical approach to treatment for valgus overcorrection in older feet treated with surgical correction pre 2000's.


Go to the Vertical Talus (Congenital) - Congenital Rocker Bottom page



Dr. Ponseti's Studies

The 30 Year Study

(that fueled the parental revolution and was the inspiration for Dr. Ponseti's book, Congenital Clubfoot: Fundamentals of Treatment, published in 1996)


Modification vs Strict Adherence to Ponseti Method

Clubfoot In History

Ponseti Method Training



Does the Ponseti Method for Clubfoot Treatment Stand Up to the March of Time? Commentary on an article by Lewis E. Zionts, MD, et al.: “Sixty Years On: Ponseti Method for Clubfoot Treatment Produces High Satisfaction Despite Inherent Tendency to Relapse” - Letts, R. Mervyn MD, MSc, FRCSCa




Valgus Overcorrection



*See the "Neglected Clubfoot" section for papers studying the Ponseti Method for children of walking age, or older.









Flat-Top Talus

Talar Deformity




Accelerated or "Fast" Casting



.


"The goal of the extensive bracing regime is to prevent recurrence by opposing the deforming forces at the medial ankle–foot joints that persist or reoccur after initial correction of the clubfoot" (Ponseti 2002, Dobbs and Gurnett 2009, Hosseinzadeh et al. 2017).

NOTE: This paper has important information about bracing and relapse


Bracing Comparisons


Foot Abduction Brace/Bar (FAB, BnB, Boots & Bar, DBB)


Bracing Time/Length & Compliance


Abduction Dorsiflexion Mechanism (ADM)

ADM prospective studies

*This is not a published paper or confirmed study; but it might be ongoing. If you wish to participate see this page and email the study contact.
Feasibility of Other Orthosis for Talipes (FOOT) trial - Nigel Kiely - United Kingdom


Ankle Foot Orthosis (AFO)



NOTE: This paper discusses relapse as associated with Pirani and Dimeglio scores

NOTE: This paper shows awesome images of what relapse looks like.

Note: This paper uses data from Pirani score, number of casts, and bracing compliance to get their results. Therefore it will be listed in 3 categories on this page.


Relapse Assessment


Clubfoot Relapse Surgery (Anterior Tibialis Tendon Transfer - ATTT/TATT/ATT)

NOTE: This full text paper shows both still images and video of the ATTT surgery

Other Relapse Surgery


Clubfoot Severity Scoring/Classification (initial assessment)

letter to the editor re: Predicting the Need for Surgical Intervention in Patients With Idiopathic Clubfoot June 2016 - Aydin, Bahattin K. MD; Sofu, Hakan MD


Ultrasound Assessment of Clubfoot Severity


Clubfoot Assessment (after treatment)



Associated Risk Factors (potential)


NOTE: This study used AFO's for both groups. AFO as a brace for feet corrected with the Ponseti Method is shown to be ineffective. See the Bracing Studies section above > sub-section AFO. This paper's results show positive results for the Ponseti group, but we believe using AFO for bracing post casting is a modification of the Ponseti Method, and as such likely skews the success rates significantly.


Arthrogryposis


Myelomeningocele


Spina Bifida


Tethered Cord

Amniotic Band Syndrome


Polydactyly


Developmental Hip Dysplasia, Congenital Muscular Torticollis

Other specific disorders or conditions

  • Saul-Wilson Syndrome - Carlos Ferreira Margaret P Adam, David B Everman, Ghayda M Mirzaa, Roberta A Pagon, Stephanie E Wallace, Lora JH Bean, Karen W Gripp, Anne Amemiya, editors. - GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993. 2020 Feb 20.

  • **Studies associated with initial surgical correction - Non-Ponseti Method. Some are quite old, Some do not have text at all. Full texts can usually be specifically requested.


    Multi-Method Comparisons


    French Functional


    Copenhagen

    Ram's Taping


    Kite

    Others


    **Clubfoot is often left untreated in some underdeveloped nations and it can take some years to begin treatment. Usually patients are over 6 months to a year old, but often they are much older.

    NOTE: This paper follows a 24 year old untreated/neglected university student treated with Ponseti Method

    Iliazarov Technique/Frame/External Fixators




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